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Position: Scientist and Senior Resident

Qualification: B.Sc. (Biotechnology); M.Sc. (Biotechnology); Ph.D.

Orcid : https://orcid.org/0000-0002-6811-9767

Email-ID: naha.aniket4@gmail.com; draniketnaha@pimsrc.edu.in

Mobile:+91-8473912790

Land Line: +91 469 2731005, +91 469 2700755  Ext: 7605

ResearchGate: https://www.researchgate.net/profile/Aniket-Naha

Research Areas

Biotechnology; Microbiology; Bioinformatics

    1. The emergence of antimicrobial tolerance and resistance in ESKAPE pathogens
    2. Phenotypic-molecular characterisation, biofilm assay, quorum sensing and screening of potential biofilm disrupters
    3. Screening of effective antimicrobial agents derived from phytocompounds
    4. Elucidating the underlying mechanisms in inhibition of advanced glycation end-products (AGE) causing chronic diabetic complications using phytocompound derivatives
    5. Bioelectricity production through Microbial Fuel Cells (MFC) from hospital wastes/wastewater treatment plants
    6. Systems biology approaches using protein-protein interaction (PPI) and host-pathogen interaction (HPI) to reveal alternate therapeutic biomarkers in nosocomial pathogens
    7. Virtual screening, pharmacokinetics-pharmacodynamics (PK-PD) assessments, pharmacophore modelling and lead optimisation through quantum chemical density functional theory simulation.
    8. Structural bioinformatics approaches to validate the stability of novel theranostic biomarkers with screened leads through molecular docking, molecular and essential dynamics simulation.

 

Important publications

  1. Aniket Naha, Sherly Antony, Soumitra Nath, Dhrubjyoti Sharma, Anamika Mishra, Devika T. Biju, Aravind Madhavan, Parameswaran Binod, Sunita Varjani, and Raveendran Sindhu. “A hypothetical model of multi-layered cost-effective wastewater treatment plant integrating microbial fuel cell and nanofiltration technology: A comprehensive review on wastewater treatment and sustainable remediation.” Environmental Pollution(2023): 121274. https://doi.org/10.1016/j.envpol.2023.121274. [Impact Factor: 988]
  2. Aniket Naha, Sanjukta Banerjee, Reetika Debroy, Soumya Basu, Gayathri Ashok, P. Priyamvada, Hithesh Kumar, et al. 2022. “Network Metrics, Structural Dynamics and Density Functional Theory Calculations Identified a Novel Ursodeoxycholic Acid Derivative against Therapeutic Target Parkin for Parkinson’s Disease.” Computational and Structural Biotechnology Journal 20: 4271–87. https://doi.org/10.1016/j.csbj.2022.08.017. [Impact Factor: 155]
  3. Aniket Naha, and Sudha Ramaiah. 2022. “Structural Chemistry and Molecular-Level Interactome Reveals Histidine Kinase EvgS to Subvert Both Antimicrobial Resistance and Virulence in Shigella flexneri 2a Str. 301.” 3 Biotech 12 (10): 258. https://doi.org/10.1007/s13205-022-03325-w. [Impact Factor: 893]
  4. Aniket Naha, Saranya Vijayakumar, Binesh Lal, Baby A. Shankar, Suriya Chandran, Sudha Ramaiah, Balaji Veeraraghavan, and Anand Anbarasu. 2021. “Genome Sequencing and Molecular Characterisation of XDR Acinetobacter baumannii Reveal Complexities in Resistance: Novel Combination of Sulbactam–Durlobactam Holds Promise for Therapeutic Intervention.” Journal of Cellular Biochemistry 122 (12): 1946–57. https://doi.org/10.1002/jcb.30156. [Impact Factor: 480]
  5. Aniket Naha, Sravan Kumar Miryala, Reetika Debroy, Sudha Ramaiah, and Anand Anbarasu. 2020. “Elucidating the Multi-Drug Resistance Mechanism of Enterococcus faecalis V583: A Gene Interaction Network Analysis.” Gene 748 (July): 144704. https://doi.org/10.1016/j.gene.2020.144704. [Impact Factor: 913]
  6. Aniket Naha, Dipen Chandra Nath, and Soumitra Nath. 2020. “Impact of Pesticides on the Growth of Coriandrum sativum.” International Journal of Plant Physiology and Biochemistry 12 (1): 17–25. https://doi.org/10.5897/IJPPB2020.0301.
  7. Soumya Basu, Aniket Naha, Balaji Veeraraghavan, Sudha Ramaiah, and Anand Anbarasu. 2022. “In Silico Structure Evaluation of BAG3 and Elucidating Its Association with Bacterial Infections through Protein-Protein and Host-Pathogen Interaction Analysis.” Journal of Cellular Biochemistry 123 (1): 115–27. https://doi.org/10.1002/jcb.29953. [Impact Factor: 480]
  8. Soumitra Nath, Aniket Naha, and Mehdi Hasan Choudhury. 2020. “Mapping the Molecular Basis and Preventive Strategies of Covid-19: A Review towards Evoking Public Awareness.” In Biological Sciences: Impacts on Modern Civilization, Current and Future Challenges, 103–17. New Delhi Publishers. https://doi.org/10.30954/ndp.bio.2020.9. [Book Chapter]
  9. Reetika Debroy, Sravan Kumar Miryala, Aniket Naha, Anand Anbarasu, and Sudha Ramaiah. 2020. “Gene Interaction Network Studies to Decipher the Multi-Drug Resistance Mechanism in Salmonella Enterica Serovar Typhi CT18 Reveal Potential Drug Targets.” Microbial Pathogenesis 142 (February): 104096. https://doi.org/10.1016/j.micpath.2020.104096. [Impact Factor: 848]
  10. Sravan Kumar Miryala, Soumya Basu, Aniket Naha, Reetika Debroy, Sudha Ramaiah, Anand Anbarasu, and Saravanan Natarajan. 2021. “Identification of Bioactive Natural Compounds as Efficient Inhibitors against Mycobacterium tuberculosis Protein-Targets: A Molecular Docking and Molecular Dynamics Simulation Study.” Journal of Molecular Liquids 341 (November): 117340. https://doi.org/10.1016/j.molliq.2021.117340. [Impact Factor: 633]
  11. Deepshikha Bhowmik, Shiela Chetri, Kingsley Erhons Enerijiofi, Aniket Naha, Tushar Deb Kanungo, Maulin P. Shah, and Soumitra Nath. “Multitudinous approaches, challenges and opportunities of bioelectrochemical systems in conversion of waste to energy from wastewater treatment plants.” Cleaner and Circular Bioeconomy(2023): 100040. https://doi.org/10.1016/j.clcb.2023.100040
  12. Sravan Kumar Miryala, Soumya Basu, Aniket Naha, Reetika Debroy, Sudha Ramaiah, Anand Anbarasu, and Saravanan Natarajan. 2022. “Datasets Comprising the Quality Validations of Simulated Protein-Ligand Complexes and SYBYL Docking Scores of Bioactive Natural Compounds as Inhibitors of Mycobacterium tuberculosis Protein-Targets.” Data in Brief 42 (June): 108146. https://doi.org/10.1016/j.dib.2022.108146.
  13. Karthick Vasudevan, Soumya Basu, Amala Arumugam, Aniket Naha, Sudha Ramaiah, Anand Anbarasu, and Balaji Veeraraghavan. 2021. “Identification of Potential Carboxylic Acid-Containing Drug Candidate to Design Novel Competitive NDM Inhibitors: An in-Silico Approach Comprising Combined Virtual Screening and Molecular Dynamics Simulation.” Researchsqaure Preprint. https://doi.org/10.21203/rs.3.rs-784343/v1.

Work experience

  1. ICMR Research Assistant: Vellore Institute of Technology, Vellore (2019-2022)
  2. Visiting Researcher: Christian Medical College and Hospital, Vellore (2019-2022)
  3. Research and Development Employee: Eurofins Advinus Ltd, Bengaluru (2018-2019)
  4. Post Graduate Dissertation: Vellore Institute of Technology, Vellore (2018-2019)
  5. Research Intern: Indian Institute of Technology, Guwahati (2018)

Major Career Achievements

  1. ‘Research Fellowship’ from Indian Council of Medical Research (ICMR), New Delhi (2019-2022)
  2. ‘Best Oral Presentation’ at ICCAR-2021, Acharya Institutes, Bengaluru (2021)
  3. ‘Merit Scholarship’ for M.Sc. Biotechnology at Vellore Institute of Technology, Vellore (2017-2019)
  4. ‘Gold Medalist-Best Graduate’ in B.Sc. Biotechnology awarded by Assam University, Silchar (2014-2017)

Funded projects

  1. Project Title: Genomic and systems biology studies to understand the mechanism of multi drug resistant pathogenic bacterial spp. of clinical importance

Funded by: Indian Council of Medical Research (ICMR)-New Delhi

  1. Project Title: Bioinformatics and molecular approaches to characterize the mechanism of multi-drug resistance in Salmonella typhirecovered from children (<15 years) with typhoid at a paediatric speciality teaching hospital

Funded by: Indian Council of Medical Research (ICMR)-New Delhi

  1. Project Title: Deciphering the efficacy of emerging therapeutic agents against multi-drug resistant ESKAPE pathogens through molecular characterization, systems and structural biology

Funded by: Indian Council of Medical Research (ICMR)-New Delhi

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