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Dr. Aniket Naha

Dr. Aniket Naha

Scientist & Student Coordinator

Qualifications

B.Sc. (Gold Medalist-Best Graduate); M.Sc.; Ph.D.

Biotechnology; Microbiology; Bioinformatics

  1. The emergence of antimicrobial tolerance and resistance in ESKAPE pathogens
  2. Phenotypic-molecular characterisation, biofilm assay, quorum sensing and screening of potential biofilm disrupters
  3. Screening of effective antimicrobial agents derived from phytocompounds
  4. Elucidating the underlying mechanisms in inhibition of advanced glycation end-products (AGE) causing chronic diabetic complications using phytocompound derivatives
  5. Bioelectricity production through Microbial Fuel Cells (MFC) from hospital wastes/wastewater treatment plants
  6. Systems biology approaches using protein-protein interaction (PPI) and host-pathogen interaction (HPI) to reveal alternate therapeutic biomarkers in nosocomial pathogens
  7. Virtual screening, pharmacokinetics-pharmacodynamics (PK-PD) assessments, pharmacophore modelling and lead optimisation through quantum chemical density functional theory simulation.
  8. Structural bioinformatics approaches to validate the stability of novel theranostic biomarkers with screened leads through molecular docking, molecular and essential dynamics simulation.

  • Bhowmik, D., Chetri, S., Enerijiofi, K.E., Naha, A., Kanungo, T.D., Shah, M.P. and Nath, S., 2023. Multitudinous approaches, challenges and opportunities of bioelectrochemical systems in conversion of waste to energy from wastewater treatment plants. Cleaner and Circular Bioeconomy, 4, p.100040.

  • Nath, S., Astapati, A.D., Naha, A., Sharma, I. and Shah, M.P., 2024. Algal-based membrane bioreactors for effective removal of hazardous and toxic contaminants: A comprehensive review. Current Research in Biotechnology, p.100201.

  • Naha, A., Nath, D.C. and Nath, S., 2020. Impact of pesticides on the growth of Coriandrum sativum. International Journal of Plant Physiology and Biochemistry, 12(1), pp.17-25.

  • Miryala, S.K., Basu, S., Naha, A., Debroy, R., Ramaiah, S., Anbarasu, A. and Natarajan, S., 2022. Datasets comprising the quality validations of simulated protein-ligand complexes and SYBYL docking scores of bioactive natural compounds as inhibitors of Mycobacterium tuberculosis protein-targets. Data in brief, 42, p.108146.

  • Naha, A., Miryala, S.K., Debroy, R., Ramaiah, S. and Anbarasu, A., 2020. Elucidating the multi-drug resistance mechanism of Enterococcus faecalis V583: a gene interaction network analysis. Gene, 748, p.144704.

  • Naha, A. and Ramaiah, S., 2022. Structural chemistry and molecular-level interactome reveals histidine kinase EvgS to subvert both antimicrobial resistance and virulence in Shigella flexneri 2a str. 301. 3 Biotech, 12(10), p.258.

  • Naha, A., Vijayakumar, S., Lal, B., Shankar, B.A., Chandran, S., Ramaiah, S., Veeraraghavan, B. and Anbarasu, A., 2021. Genome sequencing and molecular characterisation of XDR Acinetobacter baumannii reveal complexities in resistance: Novel combination of sulbactam–durlobactam holds promise for therapeutic intervention. Journal of Cellular Biochemistry, 122(12), pp.1946-1957

  • Basu, S., Naha, A., Veeraraghavan, B., Ramaiah, S. and Anbarasu, A., 2022. In silico structure evaluation of BAG3 and elucidating its association with bacterial infections through protein–protein and host?pathogen interaction analysis. Journal of Cellular Biochemistry, 123(1), pp.115-127.

  • Debroy, R., Miryala, S.K., Naha, A., Anbarasu, A. and Ramaiah, S., 2020. Gene interaction network studies to decipher the multi-drug resistance mechanism in Salmonella enterica serovar Typhi CT18 reveal potential drug targets. Microbial pathogenesis, 142, p.104096. 

  • Naha, A., Debroy, R., Sharma, D., Shah, M.P. and Nath, S., 2023. Microbial fuel cell: A state-of-the-art and revolutionizing technology for efficient energy recovery. Cleaner and Circular Bioeconomy, 5, p.100050.

  • Naha, A. and Ramaiah, S., 2024. Novel antimicrobial peptide SAAP mutant as a better adjuvant to sulbactam-based treatments against clinical strains of XDR Acinetobacter baumannii. Probiotics and Antimicrobial Proteins, 16(2), pp.459-473.

    https://pubmed.ncbi.nlm.nih.gov/36971982/
  • Naha, A., Banerjee, S., Debroy, R., Basu, S., Ashok, G., Priyamvada, P., Kumar, H., Preethi, A.R., Singh, H., Anbarasu, A. and Ramaiah, S., 2022. Network metrics, structural dynamics and density functional theory calculations identified a novel Ursodeoxycholic Acid derivative against therapeutic target Parkin for Parkinson's disease. Computational and Structural Biotechnology Journal, 20, pp.4271-4287. 

    https://www.sciencedirect.com/science/article/pii/S2001037022003518
  • Bioelectricity Production with Triple Anodic Chamber Microbial Fuel Cells in static and Dynamic Environments – Two Days National Seminar on Recent Development in Science and Technology organised by Department of Chemistry, Karimganj College, Karimganj, Assam

  • Nath, S., Naha, A. and Chowdhury, M.H., Mapping the molecular basis and preventive strategies of Covid-19: A review towards evoking public awareness In : Biological Sciences: Impacts on Modern Civilization, Current and Future Challenges by Anupam Guha © New Delhi Publishers, New Delhi: 2020, 103-107, ISBN: 978-81-947417-9-4

    https://prc.pushpagiri.in/2022/12/05/biotechnology-bioinformatics/
  • Mishra, A., Naha, A., Soundharya H., Nath, S., Varghese, N. and Soumya, RS., Designing Novel Serine Protease Inhibitors against Potential Biomarkers Specific to Lung Adenocarcinoma through Systems Biology and Structural Bioinformatics Approaches; Handbook of Proteases in Cancer; Taylor and Francis, CRC Press

  • Naha, A., Antony, S., Nath, S., Sharma, D., Mishra, A., Biju, D.T., Madhavan, A., Binod, P., Varjani, S. and Sindhu, R., 2023. A hypothetical model of multi-layered cost-effective wastewater treatment plant integrating microbial fuel cell and nanofiltration technology: a comprehensive review on wastewater treatment and sustainable remediation. Environmental Pollution, 323, p.121274.

    https://www.sciencedirect.com/science/article/abs/pii/S0269749123002762
  • Miryala, S.K., Basu, S., Naha, A., Debroy, R., Ramaiah, S., Anbarasu, A. and Natarajan, S., 2021. Identification of bioactive natural compounds as efficient inhibitors against Mycobacterium tuberculosis protein-targets: a molecular docking and molecular dynamics simulation study. Journal of Molecular Liquids, 341, p.117340.

    https://www.sciencedirect.com/science/article/abs/pii/S016773222102064X
  • Usharani, N., Naha, A., Anbarasu, A., Ramaiah, S., Kanth, S.V. and Natarajan, S., 2023. Green synthesis and characterization of water soluble nanocarnosine: A prospective drug delivery system. Applied Materials Today, 32, p.101812.

    https://www.sciencedirect.com/science/article/abs/pii/S2352940723000823

  1. ICMR Research Assistant: Vellore Institute of Technology, Vellore (2019-2022)
  2. Visiting Researcher: Christian Medical College and Hospital, Vellore (2019-2022)
  3. Research and Development Employee: Eurofins Advinus Ltd, Bengaluru (2018-2019)
  4. Post Graduate Dissertation: Vellore Institute of Technology, Vellore (2018-2019)
  5. Research Intern: Indian Institute of Technology, Guwahati (2018)

  1. ‘Research Fellowship’ from Indian Council of Medical Research (ICMR), New Delhi (2019-2022)
  2. ‘Best Oral Presentation’ at ICCAR-2021, Acharya Institutes, Bengaluru (2021)
  3. ‘Merit Scholarship’ for M.Sc. Biotechnology at Vellore Institute of Technology, Vellore (2017-2019)
  4. ‘Gold Medalist-Best Graduate’ in B.Sc. Biotechnology awarded by Assam University, Silchar (2014-2017)

  1. Project Title: Genomic and systems biology studies to understand the mechanism of multi drug resistant pathogenic bacterial spp. of clinical importance. Funded by: Indian Council of Medical Research (ICMR)-New Delhi
  2. Project Title: Bioinformatics and molecular approaches to characterize the mechanism of multi-drug resistance in Salmonella typhirecovered from children (<15 years) with typhoid at a paediatric speciality teaching hospital. Funded by: Indian Council of Medical Research (ICMR)-New Delhi
  3. Project Title: Deciphering the efficacy of emerging therapeutic agents against multi-drug resistant ESKAPE pathogens through molecular characterization, systems and structural biology. Funded by: Indian Council of Medical Research (ICMR)-New Delhi
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