Biochemistry lab at PRC enables cutting edge results in Biochemistry and related fields. The lab gives an excellent opportunity for students to gain practical knowledge and contribute to ongong research projects. The lab offers internships, training programs and PhD programs in Biochemistry & Life sciences, also provides hands on experience on advance techniques and instruments. Dr Soumya R.S is the faculty of Biochemistry lab. Did her PHd FROM csir-niist, Trivandrum, Post Doc (DS Kothari Post Doctoral Fellowship, Govt. of India )from Dept. of Biochemistry, University of Kerala, Post Doc ( Department of Health Research, Women Scientist Fellowship, Govt. of India) from CSIR-NIIST, Trivandrum.
Dr Soumya R.S, Scientist, Pushpagiri Research Centre, has been approved as a research guide in the subject area of Medical Biochemistry by Kerala University of Health Sciences (U.O. No 262l2023/dean/KUHS dated 12/04/2023).
Approved Co-Guide (VMRF/PhDSECTION/2023-24/782 DATED 27/11/2023) of Vinayaka Mission’s Research Foundation (Deemed to be University), Salem Tamil Nadu.
Savitha D. P, Anjali K. G, Divya K. M, R S. Soumya, Raghu K. G, PV. Mohanan, Isatin derived novel Schiff bases: An efficient pharmacophore for versatile biological applications, Journal of Molecular Structure, 1271, 2023, 134121, ISSN 0022-2860.
V.P Vineetha, A. Prathapan, R. S Soumya, K. G Raghu. Arsenic trioxide toxicity in H9c2 myoblasts—damage to cell organelles and possible amelioration with Boerhavia diffusa. Cardiovascular toxicology, 2013, 13, 123-137.
V.P Vineetha, S.Girija, R.S Soumya, K.G Raghu. Polyphenol-rich apple (Malus domestica L.) peel extract attenuates arsenic trioxide induced cardiotoxicity in H9c2 cells via its antioxidant activity. Food & function, 2014, 5 (3), 502-511
V.P Vineetha, R.S Soumya, K.G Raghu. Phloretin ameliorates arsenic trioxide induced mitochondrial dysfunction in H9c2 cardiomyoblasts mediated via alterations in membrane permeability and ETC complexes European journal of pharmacology 2015, 754, 162-172
V. Sankar, P. SalinRaj, R. Athira, R.S Soumya, K.G Raghu Cerium nanoparticles synthesized using aqueous extract of Centella asiatica: characterization, determination of free radical scavenging activity and evaluation of efficacy against cardiomyoblast hypertrophy. RSC Advances 2015, 5 (27), 21074-21083.
R.S Soumya, E.T Abraham. Isolation of β-mannanase from Cocos nucifera Linn haustorium and its application in the depolymerization of β-(1, 4)-linked d-mannans International journal of food sciences and nutrition, 2010, 61, 272-281.
R.S Soumya, S. Ghosh, E.T Abraham. Preparation and characterization of guar gum nanoparticles International journal of biological macromolecules 2010, 46, 267-269.
R.S Soumya, V.P Vineetha, P.L Reshma, K.G Raghu. Preparation and characterization of selenium incorporated guar gum nanoparticle and its interaction with H9c2 cells. PloS one 2013, 8 (9), e74411
R.S Soumya, V.P Vineetha, P.S Raj, K.G Raghu. Beneficial properties of selenium incorporated guar gum nanoparticles against ischemia/reperfusion in cardiomyoblasts (H9c2) Metallomics 2014, 6, 2134-2147.
R.S Soumya, R Reshmi, S Jomon, K.A Antu, M.P Riya, K.G Raghu. Synthesis, characterization and evaluation of the antioxidant potential of vanadium encapsulated guar gum nanoparticles. Food & function. 2014, 5 (3), 535-544.
Sherin S, Sheeja S, Sudha Devi R, Balachandran S, R S Soumya, Abraham A. In vitro and in vivo pharmacokinetics and toxicity evaluation of curcumin incorporated titanium dioxide nanoparticles for biomedical applications. Chemico Biological Interaction. 2017 275, 35-46.
R S Soumya, A Prathapan, P S Raj, V P Vineetha, K G Raghu. Selenium incorporated guar gum nanoparticles safeguard mitochondrial bioenergetics during ischemia reperfusion injury in H9c2 cardiac cells. International Journal of Biological Macromolecules. 2018, 107(Pt A):254-260.
R.S Soumya, Sherin S, Raghu KG, Abraham A. Allicin functionalized locust bean gum nanoparticles for improved therapeutic efficacy: An in silico, in vitro and in vivo approach. International Journal of Biological Macromolecules. 2018, 109, 740-747.
R.S Soumya, T. Govindan Unni, KG Raghu, Impact of COVID-19 on the Cardiovascular System: A Review of Available Reports. Cardiovasc Drugs Ther. 2020, 14: 1–15 10.1007/s10557-020-07073-y.
R S Soumya, K B Raj, A Abraham. Passiflora edulis (var. Flavicarpa) Juice Supplementation Mitigates Isoproterenol-induced Myocardial Infarction in Rats. Plant Foods Hum Nutr. 2021;76(2):189-195. doi:10.1007/s11130-021-00891-x
Treesa Sani, VP Sruthi , NJ Jomol,, Nibu Varghese, RS Soumya*, Green synthesis of calcium carbonate nano scale particles using Benincasa hispida (Thunb.) Cogn. pulp and their qualities. Indian J. Exp. Biol. 2024; 62: 530-539. 10.56042/ijeb.v62i07.12074.
R S Soumya, K G Raghu. Recent advances on nanoparticle-based therapies for cardiovascular diseases. J Cardiol. 2023;81(1):10-18. doi:10.1016/j.jjcc.2022.02.009.
Book:Pathophysiological Aspects of Proteases in Cancer Chapter 33: Cathepsin responsive nanomaterials for targeted delivery of malignant tumors, Soumya R.S, George Vargeshe, Genu George, Elsevier, ISBN: 9780443300981
Book Title:Additive Manufacturing Chapter 13: Medical Additive Manufaturing- the way to the future, Devika T. Biju, Rosita Kurian R.S. Soumya, and Sherly Antony Elsevier , ISBN 978-0-323-95383-2
Book Title:Additive Manufacturing Chapter 8: Medical Additive Manufaturing-The magic wand for Cardiology, R.S. Soumya, Sherly Antony, Devika T. Biju and Rosita Kurian. Elsevier , ISBN 978-0-323-95383-2
Book Title: Phospholipase in Physiology and Pathology Vol 7, Phospholipase in nonmalignant human disease. Chapter: 15. Phospholipase activities in cardiovascular disease and its role as a potential biomarker in heart failure, R.S. Soumya & Prathapan Ayyappan, Elsevier , Academic Press, ISBN No: 978-0-443-21800-2
Book Title: “Polysaccharide-based biomaterials: Delivery of Therapeutics & Biomedical Applications”, Chapter: Locust Bean Gum-A Potential Drug Delivery Carrier, RS Soumya, KG Raghu & Annie Abraham*, The Royal Society of Chemistry (RSC), UK.ISBN:9781839164989.
Book Title: Micro and Nano Engineered Gum-Based Biomaterials for Drug Delivery and Biomedical Application; Chapter: Locust bean gum based micro and nanomaterials for biomedical applications, RS Soumya, KG Raghu & Annie Abraham*ISBN eBook ISBN: 9780323909877,Paperback ISBN: 9780323909860 Elsevier.
Workshops
Attended National level seminar on Advances in Medical Sciences. E.M.E.A College of Arts and Science. Malappuram, 29th August, 2005.
Soumya R.S and Emilia Abraham. Studies on the preparation of nanoparticles from low-molecular weight guar gum. Poster presented at International conference on New Horizons in Biotechnology. Trivandrum, 26-29 November, 2007
Soumya R.S and.Galactomannan nanoparticles for novel applications . Poster presented at National conference on Advances in Nanomaterials Devices and Technologies held at S.V Degree College , Kadapa, Andra Pradesh,11-12 July, 2009.
Soumya R.S and Emilia Abraham. Preparation and properties of galactomannan nanoparticles. Poster presented at Indian Science Congress, held at University of Kerala, Trivandrum Jan 3-7,2010.
Soumya R.S and Raghu K.G. Evaluation of guar gum nanoparticle incorporated selenium against cardiac ischemia: an in vitro cell line based approach. Poster presented at International conference on New Horizons in Biotechnology. Trivandrum, 21-24 November, 2011.
Attended State level seminar on New risk factors of Coronary Artey Diseases. N.S.S College Pandalam, 16-17 February, 2012.
Attended 25th Kerala Science Congress on 29th Jan- 1st Feb, 2013 at Technopark, Trivandrum.
Attended International seminar on recent biochemical approaches in therapeutics held at Department of Biochemistry, University of Kerala, on December 9-11,2015.
Soumya R.S and Raghu K.G. An In vitro evaluation of selenium incorporated guar gum nanoparticle against ischemia induced alterations in mitochondrial functions. Poster presented at Indo-Canadian Symposium on Heart Failure Progress and Prospects on March 12-14,2015, RGCB, Trivandrum.
Participated in the National seminar on recent biochemical approaches in therapeutics 2017 held at Department of Biochemistry, University of Kerala, on February 15-17, 2017.
Soumya R.S and Annie Abraham. Allicin functionalized locust bean bean gum nanoparticles for biomedical applications. Poster presented on 2nd Annual conference of Indian society of Nanomedicine (ISNM) NANOBIOTECK-2017 on Dec 6-8th, 2017.
Soumya R.S and Annie Abraham. Invitro and Invivo toxicity evaluation of allicin functionalized locust bean bean gum nanoparticles for therapeutic applications. Poster presented on International Conference on advances in degenerative diseases and molecular interventions (ADDMI) organised by Society For Research in Degenerative Diseases (SODD) held on Nov 23-24th ,2017
Soumya R.S and Raghu K.G. Encapsulation of selenium in guar gum nanoparticles improves selenium availability and protects cardiomyoblast from ischemia. Oral presentation at International conference on Bioactive Phytochemicals and Therapeutics- 2013. Annamalai University, Chidhamparam, 5-7 April, 2013. (Travel Grant Award).
Soumya R.S and Raghu K.G. Selenium incorporated guar gum nanoparticles protect H9c2 cardiomyoblasts from ischemia. Oral presentation at 26th annual symposium of Indian society of Atherosclerosis Research. Amala Cancer Center Thrissur, 22-23 November, 2013.
Soumya R.S and Raghu K.G. Selenium incorporated guar gum nanoparticles attenuates ischemia induced mitochondrial alteration in H9c2 cardiomyoblasts Oral presentation at International conference on Green Technology for Health and Environment: Implementation and Policies-2016, Bangalore, 15-16th December 2016.
Soumya R.S and Annie Abraham. Synthesis, Characterization and Toxicity Evaluation of Locust Bean Gum Nanoparticles Oral presentation at International conference onAdvances in Biotechnology and Biotherapeutics (ICABBS-2017), Satyabhama University, Chennai, March 08-10th 2017.
Soumya R.S and Annie Abraham. Cardioprotective Effect at CSIRct of Allicin Functionalized Locust Bean Gum Nanoparticles Aganist Isoproterenol Induced Myocardial Infarction oral presentation at National Seminar on Insights into the interdisciplinary perspectives of chemical and biosciences held at Govt Arts College, Thiruvanathapuram on 26th-28th Feb 2018.
Soumya R.S and Annie Abraham. Protective effects of allicin functionalized locust bean gum nanoparticles aganist isoproterenol induced myocardial infarction oral presentation at 16th Annual meeting of Society for Free Radical Research in India, International Conference on Translational Research in Free Radicals, Micronutrient Antioxidants ., and Functional Foods during 18-20th Feb 2018, at AIIMS, New Delhi, India.
Soumya R.S and Raghu K.G. Synthesis and Invitro evaluation of triphenylphosphonium conjugated rutin functionalized guar gum nanoparticles with enhanced cardioprotection and ability to restore mitochondrial function in hypertrophy at National seminar on recent trends in disease prevention and health management at CSIR-NIIST&Kerala Academy of Science during 14-15 December 2022.
Soumya R.S attended the CME on Bioethics organised by Pushpagiri Bioethics Unit at Pushpagiri Institute of Medical Science & Research Centre Tiruvalla on 16th November 2022.
Soumya R.S presented a paper Mitochondria as a fascinating therapeutic target during continuing medcal education session conducted by Pushpagiri Institute of Medical Science &Research centre Tiruvalla 09th August 2023.
Treesa Sani & Soumya R.S. Green synthesis of calcium carbonate nanoparticles using benincasa hispida extract and their anti-inflammatory, antioxidant and photo catalytic activity at International Conference on emerging trends and innovations in biotechnology BIOSPECTRUM 2023 at MACFAST, Thiruvalla from Nov 302023 to December 2 2023.
Soumya R.S and Annie Abraham. Effect of Allicin incorporated locust bean gum nanoparticles on isoproterenol induced myocardial infarction in rats at National conference on advanced functional materials-2023 during 23-03-2023 t024-03-2023 at VTMNSS College Dhanuvachapuram, Trivandrum.
Soumya R.S. participated as a resource person in the National Conference ‘Bioradiance 2023:Microbiome little bugs friends and foeorganized by Pushpagiri Research Centre and Department of Microbiology, Pushpagiri Institute of medical Science and Research Centre Thiruvalla, on 27th May 2023.
Treesa Sani & Soumya R.S. Synthesis of nanoparticles of vanadium as potent antioxidants: an in vitro approach at National Conference on OMICS in redefining healthcare at Jubilee Centre for Medical Research Thrissur from 23& 24August 2024.